Ozempic is a separate drug used as monotherapy for type 2 diabetes. It lowers blood sugar level by simulating the action of the natural hormone GLP-1, which promotes insulin secretion.
Januvia — DDP-4 inhibitor. This medicine is an adjunct to other medicines in treating type 2 diabetes.
|
Ozempic |
Januvia |
| Active substance |
Semaglutide |
Sitagliptin |
| Dosage form |
Subcutaneous injection solution |
Oral tablets |
| Drug class |
Incretin mimetics |
Dipeptidyl peptidase 4 inhibitors |
| Main side effects |
- Low blood sugar (people with type 2 diabetes);
- Headache;
- Diarrhea, constipation;
- Heartburn;
- Nausea, vomiting;
- Abdominal pain;
- Dizziness.
|
- Upper respiratory tract infection;
- Cold in the head;
- Sore throat;
- Headache.
|
| Other brand names |
Rybelsus, Wegovy |
No |
| Generic availability |
No |
No |
| Half-life period |
168 hours |
12 hours |
| Interaction with other drugs |
245. Of these, 2 serious, 222 moderate and 21 minor ones |
275. Of these, 2 serious, 251 moderate and 24 minor ones |
| Interaction with alcohol |
It is recommended to exclude alcohol or drink it in minimal doses completely: 1 dose per day for women and 2 doses for men (1 dose is 5 ounces of wine or 12 ounces of beer or 1.5 ounces of distilled spirits) |
| Caution with the following diseases |
- Suicidal behaviour and thoughts;
- Family and/or personal history of thyroid cancer;
- Endocrine neoplasia (tumours in the glands);
- Diabetic ketoacidosis;
- Retinopathy;
- Pancreatitis;
- Hypoglycemia
|
- Pancreatitis;
- Kidney dysfunction;
- High levels of triglycerides in the blood;
- History of alcoholism.
|
You can use these two drugs
together in complex therapy.
Of course, they have different effectiveness. See a
study that lasted 56 weeks. During the study, scientists compared Ozempic and Januvia in combination with metformin. In this combination, Ozempic was almost twice as effective as Januvia.
Conclusion
Both drugs are for treating people with type 2 diabetes, but they belong to different drug classes.
Ozempic is a separate drug. They use Januvia in complex treatment with other medications.
Ozempic is available as injector pens. Januvia is an oral tablet.
